Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ZCRB1-20-RE | 20 (40 μL) | 200 μL |  |
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| ZCRB1-20-OR | 20 (40 μL) | 200 μL |  |
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| ZCRB1-20-GO | 20 (40 μL) | 200 μL |  |
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| ZCRB1-20-GR | 20 (40 μL) | 200 μL |  |
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| ZCRB1-20-AQ | 20 (40 μL) | 200 μL |  |
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Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing. [provided by RefSeq, Jul 2008]
Gene Symbol : ZCRB1
Gene Name : Zinc finger CCHC-type and RNA binding motif containing 1
Chromosome : CHR 12: 423,261,29-423,120,85
Locus : 12q12
Alt. Genes : PREB
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