This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| VAV3-20-RE | 20 (40 μL) | 200 μL |  |
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| VAV3-20-OR | 20 (40 μL) | 200 μL |  |
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| VAV3-20-GO | 20 (40 μL) | 200 μL |  |
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| VAV3-20-GR | 20 (40 μL) | 200 μL |  |
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| VAV3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : VAV3
Gene Name : Vav guanine nucleotide exchange factor 3
Chromosome : CHR 1: 107,964,922-107,571,159
Locus : 1p13.3
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