The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UBE2M-20-RE | 20 (40 μL) | 200 μL |  |
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| UBE2M-20-OR | 20 (40 μL) | 200 μL |  |
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| UBE2M-20-GO | 20 (40 μL) | 200 μL |  |
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| UBE2M-20-GR | 20 (40 μL) | 200 μL |  |
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| UBE2M-20-AQ | 20 (40 μL) | 200 μL |  |
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. [provided by RefSeq, Jul 2008]
Gene Symbol : UBE2M
Gene Name : Ubiquitin conjugating enzyme E2 M
Chromosome : CHR 19: 585,589,75-585,557,11
Locus : 19q13.43
Alt. Genes : CLEC3A
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