The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UBE2J1-20-RE | 20 (40 μL) | 200 μL |  |
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| UBE2J1-20-OR | 20 (40 μL) | 200 μL |  |
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| UBE2J1-20-GO | 20 (40 μL) | 200 μL |  |
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| UBE2J1-20-GR | 20 (40 μL) | 200 μL |  |
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| UBE2J1-20-AQ | 20 (40 μL) | 200 μL |  |
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system. [provided by RefSeq, Jul 2008]
Gene Symbol : UBE2J1
Gene Name : Ubiquitin conjugating enzyme E2 J1
Chromosome : CHR 6: 893,529,16-893,266,24
Locus : 6q15
Alt. Genes : FEM1B
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