U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| U2AF2-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| U2AF2-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| U2AF2-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| U2AF2-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| U2AF2-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. [provided by RefSeq, Jul 2008]
Gene Symbol : U2AF2
Gene Name : U2 small nuclear RNA auxiliary factor 2
Chromosome : CHR 19: 556,540,49-556,747,15
Locus : 19q13.42
Alt. Genes : OPTN
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.