Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TSTA3-20-RE | 20 (40 μL) | 200 μL |  |
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| TSTA3-20-OR | 20 (40 μL) | 200 μL |  |
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| TSTA3-20-GO | 20 (40 μL) | 200 μL |  |
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| TSTA3-20-GR | 20 (40 μL) | 200 μL |  |
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| TSTA3-20-AQ | 20 (40 μL) | 200 μL |  |
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Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq, Jul 2008]
Gene Symbol : TSTA3
Gene Name : Tissue specific transplantation antigen P35B
Chromosome : CHR 8: 143,618,042-143,612,617
Locus : 8q24.3
Alt. Genes : TRAP1
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