The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53. [provided by RefSeq, Jan 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRIP12-20-RE | 20 (40 μL) | 200 μL |  |
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| TRIP12-20-OR | 20 (40 μL) | 200 μL |  |
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| TRIP12-20-GO | 20 (40 μL) | 200 μL |  |
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| TRIP12-20-GR | 20 (40 μL) | 200 μL |  |
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| TRIP12-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53. [provided by RefSeq, Jan 2017]
Gene Symbol : TRIP12
Gene Name : Thyroid hormone receptor interactor 12
Chromosome : CHR 2: 229,923,233-229,763,836
Locus : 2q36.3
Alt. Genes : HIPK3
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