This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. [provided by RefSeq, Aug 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRAF3IP2-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| TRAF3IP2-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| TRAF3IP2-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| TRAF3IP2-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| TRAF3IP2-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. [provided by RefSeq, Aug 2009]
Gene Symbol : TRAF3IP2
Gene Name : TRAF3 interacting protein 2
Chromosome : CHR 6: 111,606,873-111,555,377
Locus : 6q21
Alt. Genes : OPTN
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.