TPO FISH Probe

This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
TPO-20-RE 20 (40 μL) 200 μL color Request Pricing
TPO-20-OR 20 (40 μL) 200 μL color Request Pricing
TPO-20-GO 20 (40 μL) 200 μL color Request Pricing
TPO-20-GR 20 (40 μL) 200 μL color Request Pricing
TPO-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]

Gene Details

Gene Symbol : TPO

Gene Name : Thyroid peroxidase

Chromosome : CHR 2: 141,346,0-154,272,8

Locus : 2p25.3

Alt. Genes : LINC01587

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