This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TNFAIP3-20-RE | 20 (40 μL) | 200 μL |  |
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| TNFAIP3-20-OR | 20 (40 μL) | 200 μL |  |
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| TNFAIP3-20-GO | 20 (40 μL) | 200 μL |  |
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| TNFAIP3-20-GR | 20 (40 μL) | 200 μL |  |
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| TNFAIP3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012]
Gene Symbol : TNFAIP3
Gene Name : TNF alpha induced protein 3
Chromosome : CHR 6: 137,866,316-137,883,313
Locus : 6q23.3
Alt. Genes : FEM1B
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