This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides. [provided by RefSeq, Jan 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TMX1-20-RE | 20 (40 μL) | 200 μL |  |
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| TMX1-20-OR | 20 (40 μL) | 200 μL |  |
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| TMX1-20-GO | 20 (40 μL) | 200 μL |  |
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| TMX1-20-GR | 20 (40 μL) | 200 μL |  |
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| TMX1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides. [provided by RefSeq, Jan 2017]
Gene Symbol : TMX1
Gene Name : Thioredoxin related transmembrane protein 1
Chromosome : CHR 14: 512,401,67-512,576,54
Locus : 14q22.1
Alt. Genes : TRAP1
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