The protein encoded by this gene is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine. This creates dTMP and is the first step in the biosynthesis of dTTP, which is one component required for DNA replication. The encoded protein, whose levels fluctuate depending on the cell cycle stage, can act as a low activity dimer or a high activity tetramer. High levels of this protein have been used as a biomarker for diagnosing and categorizing many types of cancers. [provided by RefSeq, Oct 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TK1-20-RE | 20 (40 μL) | 200 μL |  |
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| TK1-20-OR | 20 (40 μL) | 200 μL |  |
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| TK1-20-GO | 20 (40 μL) | 200 μL |  |
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| TK1-20-GR | 20 (40 μL) | 200 μL |  |
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| TK1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine. This creates dTMP and is the first step in the biosynthesis of dTTP, which is one component required for DNA replication. The encoded protein, whose levels fluctuate depending on the cell cycle stage, can act as a low activity dimer or a high activity tetramer. High levels of this protein have been used as a biomarker for diagnosing and categorizing many types of cancers. [provided by RefSeq, Oct 2016]
Gene Symbol : TK1
Gene Name : Thymidine kinase 1
Chromosome : CHR 17: 781,872,07-781,740,78
Locus : 17q25.3
Alt. Genes : HIPK3
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