This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TGFBI-20-RE | 20 (40 μL) | 200 μL |  |
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| TGFBI-20-OR | 20 (40 μL) | 200 μL |  |
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| TGFBI-20-GO | 20 (40 μL) | 200 μL |  |
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| TGFBI-20-GR | 20 (40 μL) | 200 μL |  |
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| TGFBI-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]
Gene Symbol : TGFBI
Gene Name : Transforming growth factor beta induced
Chromosome : CHR 5: 136,028,894-136,063,817
Locus : 5q31.1
Alt. Genes : ENAM
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