The tectorial membrane is an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. Alpha-tectorin is one of the major noncollagenous components of the tectorial membrane. Mutations in the TECTA gene have been shown to be responsible for autosomal dominant nonsyndromic hearing impairment and a recessive form of sensorineural pre-lingual non-syndromic deafness. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TECTA-20-RE | 20 (40 μL) | 200 μL |  |
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| TECTA-20-OR | 20 (40 μL) | 200 μL |  |
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| TECTA-20-GO | 20 (40 μL) | 200 μL |  |
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| TECTA-20-GR | 20 (40 μL) | 200 μL |  |
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| TECTA-20-AQ | 20 (40 μL) | 200 μL |  |
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The tectorial membrane is an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. Alpha-tectorin is one of the major noncollagenous components of the tectorial membrane. Mutations in the TECTA gene have been shown to be responsible for autosomal dominant nonsyndromic hearing impairment and a recessive form of sensorineural pre-lingual non-syndromic deafness. [provided by RefSeq, Jul 2008]
Gene Symbol : TECTA
Gene Name : Tectorin alpha
Chromosome : CHR 11: 121,102,665-121,190,805
Locus : 11q23.3
Alt. Genes : LRPPRC
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