This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human homolog of mouse Tbx4, which is closely linked to Tbx2 on mouse chromosome 11. Similarly this gene, like TBX2, maps to human chromosome 17. Expression studies in mouse and chicken show that Tbx4 is expressed in developing hindlimb, but not in forelimb buds, suggesting a role for this gene in regulating limb development and specification of limb identity. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TBX4-20-RE | 20 (40 μL) | 200 μL |  |
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| TBX4-20-OR | 20 (40 μL) | 200 μL |  |
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| TBX4-20-GO | 20 (40 μL) | 200 μL |  |
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| TBX4-20-GR | 20 (40 μL) | 200 μL |  |
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| TBX4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human homolog of mouse Tbx4, which is closely linked to Tbx2 on mouse chromosome 11. Similarly this gene, like TBX2, maps to human chromosome 17. Expression studies in mouse and chicken show that Tbx4 is expressed in developing hindlimb, but not in forelimb buds, suggesting a role for this gene in regulating limb development and specification of limb identity. [provided by RefSeq, Jul 2008]
Gene Symbol : TBX4
Gene Name : T-box 4
Chromosome : CHR 17: 614,524,17-614,851,09
Locus : 17q23.2
Alt. Genes : ARL4C
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