This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TBX3-20-RE | 20 (40 μL) | 200 μL |  |
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| TBX3-20-OR | 20 (40 μL) | 200 μL |  |
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| TBX3-20-GO | 20 (40 μL) | 200 μL |  |
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| TBX3-20-GR | 20 (40 μL) | 200 μL |  |
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| TBX3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008]
Gene Symbol : TBX3
Gene Name : T-box 3
Chromosome : CHR 12: 114,684,163-114,670,253
Locus : 12q24.21
Alt. Genes : TRAP1
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