This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TBX19-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| TBX19-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| TBX19-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| TBX19-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| TBX19-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. [provided by RefSeq, Jul 2008]
Gene Symbol : TBX19
Gene Name : T-box 19
Chromosome : CHR 1: 168,281,039-168,314,425
Locus : 1q24.2
Alt. Genes : OPTN
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.