This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| STEAP2-20-RE | 20 (40 μL) | 200 μL |  |
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| STEAP2-20-OR | 20 (40 μL) | 200 μL |  |
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| STEAP2-20-GO | 20 (40 μL) | 200 μL |  |
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| STEAP2-20-GR | 20 (40 μL) | 200 μL |  |
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| STEAP2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Symbol : STEAP2
Gene Name : STEAP2 metalloreductase
Chromosome : CHR 7: 902,116,85-902,434,07
Locus : 7q21.13
Alt. Genes : ZNF263
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