The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| STAM2-20-RE | 20 (40 μL) | 200 μL |  |
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| STAM2-20-OR | 20 (40 μL) | 200 μL |  |
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| STAM2-20-GO | 20 (40 μL) | 200 μL |  |
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| STAM2-20-GR | 20 (40 μL) | 200 μL |  |
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| STAM2-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008]
Gene Symbol : STAM2
Gene Name : Signal transducing adaptor molecule 2
Chromosome : CHR 2: 152,175,991-152,116,800
Locus : 2q23.3
Alt. Genes : PREB
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