This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SRY-20-RE | 20 (40 μL) | 200 μL |  |
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| SRY-20-OR | 20 (40 μL) | 200 μL |  |
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| SRY-20-GO | 20 (40 μL) | 200 μL |  |
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| SRY-20-GR | 20 (40 μL) | 200 μL |  |
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| SRY-20-AQ | 20 (40 μL) | 200 μL |  |
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This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008]
Gene Symbol : SRY
Gene Name : Sex determining region Y
Chromosome : CHR Y: 278,774,0-278,685,4
Locus : Yp11.2
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