This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SRD5A2-20-RE | 20 (40 μL) | 200 μL |  |
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| SRD5A2-20-OR | 20 (40 μL) | 200 μL |  |
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| SRD5A2-20-GO | 20 (40 μL) | 200 μL |  |
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| SRD5A2-20-GR | 20 (40 μL) | 200 μL |  |
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| SRD5A2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008]
Gene Symbol : SRD5A2
Gene Name : Steroid 5 alpha-reductase 2
Chromosome : CHR 2: 316,656,50-315,224,85
Locus : 2p23.1
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