Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTA is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPTSSA-20-RE | 20 (40 μL) | 200 μL |  |
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| SPTSSA-20-OR | 20 (40 μL) | 200 μL |  |
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| SPTSSA-20-GO | 20 (40 μL) | 200 μL |  |
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| SPTSSA-20-GR | 20 (40 μL) | 200 μL |  |
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| SPTSSA-20-AQ | 20 (40 μL) | 200 μL |  |
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Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTA is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010]
Gene Symbol : SPTSSA
Gene Name : Serine palmitoyltransferase small subunit A
Chromosome : CHR 14: 344,622,61-344,329,37
Locus : 14q13.1
Alt. Genes : RASA4
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