This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPI1-20-RE | 20 (40 μL) | 200 μL |  |
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| SPI1-20-OR | 20 (40 μL) | 200 μL |  |
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| SPI1-20-GO | 20 (40 μL) | 200 μL |  |
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| SPI1-20-GR | 20 (40 μL) | 200 μL |  |
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| SPI1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : SPI1
Gene Name : Spi-1 proto-oncogene
Chromosome : CHR 11: 473,956,39-473,548,57
Locus : 11p11.2
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