This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SP140-20-RE | 20 (40 μL) | 200 μL |  |
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| SP140-20-OR | 20 (40 μL) | 200 μL |  |
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| SP140-20-GO | 20 (40 μL) | 200 μL |  |
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| SP140-20-GR | 20 (40 μL) | 200 μL |  |
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| SP140-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]
Gene Symbol : SP140
Gene Name : SP140 nuclear body protein
Chromosome : CHR 2: 230,202,923-230,316,570
Locus : 2q37.1
Alt. Genes : SORBS1
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