This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SOSTDC1-20-RE | 20 (40 μL) | 200 μL |  |
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| SOSTDC1-20-OR | 20 (40 μL) | 200 μL |  |
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| SOSTDC1-20-GO | 20 (40 μL) | 200 μL |  |
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| SOSTDC1-20-GR | 20 (40 μL) | 200 μL |  |
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| SOSTDC1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. [provided by RefSeq, Jul 2008]
Gene Symbol : SOSTDC1
Gene Name : Sclerostin domain containing 1
Chromosome : CHR 7: 164,965,12-164,614,80
Locus : 7p21.2
Alt. Genes : SGK2
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