This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SNX1-20-RE | 20 (40 μL) | 200 μL |  |
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| SNX1-20-OR | 20 (40 μL) | 200 μL |  |
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| SNX1-20-GO | 20 (40 μL) | 200 μL |  |
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| SNX1-20-GR | 20 (40 μL) | 200 μL |  |
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| SNX1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Symbol : SNX1
Gene Name : Sorting nexin 1
Chromosome : CHR 15: 640,940,70-641,442,33
Locus : 15q22.31
Alt. Genes : LRPPRC
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