The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SNUPN-20-RE | 20 (40 μL) | 200 μL |  |
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| SNUPN-20-OR | 20 (40 μL) | 200 μL |  |
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| SNUPN-20-GO | 20 (40 μL) | 200 μL |  |
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| SNUPN-20-GR | 20 (40 μL) | 200 μL |  |
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| SNUPN-20-AQ | 20 (40 μL) | 200 μL |  |
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The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : SNUPN
Gene Name : Snurportin 1
Chromosome : CHR 15: 756,263,77-755,980,82
Locus : 15q24.2
Alt. Genes : ARPC2
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