This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC12A6-20-RE | 20 (40 μL) | 200 μL |  |
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| SLC12A6-20-OR | 20 (40 μL) | 200 μL |  |
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| SLC12A6-20-GO | 20 (40 μL) | 200 μL |  |
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| SLC12A6-20-GR | 20 (40 μL) | 200 μL |  |
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| SLC12A6-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq, Jul 2008]
Gene Symbol : SLC12A6
Gene Name : Solute carrier family 12 member 6
Chromosome : CHR 15: 343,380,63-342,299,95
Locus : 15q14
Alt. Genes : FAM13A
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