This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC10A2-20-RE | 20 (40 μL) | 200 μL |  |
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| SLC10A2-20-OR | 20 (40 μL) | 200 μL |  |
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| SLC10A2-20-GO | 20 (40 μL) | 200 μL |  |
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| SLC10A2-20-GR | 20 (40 μL) | 200 μL |  |
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| SLC10A2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010]
Gene Symbol : SLC10A2
Gene Name : Solute carrier family 10 member 2
Chromosome : CHR 13: 103,066,845-103,043,997
Locus : 13q33.1
Alt. Genes : LRPPRC
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