This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SH2B3-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| SH2B3-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| SH2B3-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| SH2B3-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| SH2B3-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Gene Symbol : SH2B3
Gene Name : SH2B adaptor protein 3
Chromosome : CHR 12: 111,405,105-111,451,622
Locus : 12q24.12
Alt. Genes : FEM1B
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.