This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SFRP1-20-RE | 20 (40 μL) | 200 μL |  |
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| SFRP1-20-OR | 20 (40 μL) | 200 μL |  |
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| SFRP1-20-GO | 20 (40 μL) | 200 μL |  |
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| SFRP1-20-GR | 20 (40 μL) | 200 μL |  |
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| SFRP1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009]
Gene Symbol : SFRP1
Gene Name : Secreted frizzled related protein 1
Chromosome : CHR 8: 413,094,70-412,619,56
Locus : 8p11.21
Alt. Genes : PREB
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