This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SETMAR-20-RE | 20 (40 μL) | 200 μL |  |
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| SETMAR-20-OR | 20 (40 μL) | 200 μL |  |
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| SETMAR-20-GO | 20 (40 μL) | 200 μL |  |
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| SETMAR-20-GR | 20 (40 μL) | 200 μL |  |
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| SETMAR-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Symbol : SETMAR
Gene Name : SET domain and mariner transposase fusion gene
Chromosome : CHR 3: 430,330,3-432,064,8
Locus : 3p26.1
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