The protein encoded by this gene is a member of the ov-serpin family of serine protease inhibitors. The encoded protein is produced by platelets and can bind to and inhibit the function of furin, a serine protease involved in platelet functions. In addition, this protein has been found to enhance the mechanical stability of cell-cell adhesion in the skin, and defects in this gene have been associated with an autosomal-recessive form of exfoliative ichthyosis. [provided by RefSeq, Jan 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SERPINB8-20-RE | 20 (40 μL) | 200 μL |  |
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| SERPINB8-20-OR | 20 (40 μL) | 200 μL |  |
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| SERPINB8-20-GO | 20 (40 μL) | 200 μL |  |
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| SERPINB8-20-GR | 20 (40 μL) | 200 μL |  |
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| SERPINB8-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the ov-serpin family of serine protease inhibitors. The encoded protein is produced by platelets and can bind to and inhibit the function of furin, a serine protease involved in platelet functions. In addition, this protein has been found to enhance the mechanical stability of cell-cell adhesion in the skin, and defects in this gene have been associated with an autosomal-recessive form of exfoliative ichthyosis. [provided by RefSeq, Jan 2017]
Gene Symbol : SERPINB8
Gene Name : Serpin family B member 8
Chromosome : CHR 18: 639,700,27-640,197,78
Locus : 18q22.1
Alt. Genes : SAP18
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