Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SEMA4G-20-RE | 20 (40 μL) | 200 μL |  |
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| SEMA4G-20-OR | 20 (40 μL) | 200 μL |  |
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| SEMA4G-20-GO | 20 (40 μL) | 200 μL |  |
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| SEMA4G-20-GR | 20 (40 μL) | 200 μL |  |
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| SEMA4G-20-AQ | 20 (40 μL) | 200 μL |  |
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Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Gene Symbol : SEMA4G
Gene Name : Semaphorin 4G
Chromosome : CHR 10: 100,969,482-100,985,617
Locus : 10q24.31
Alt. Genes : LRPPRC
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