The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SEC63-20-RE | 20 (40 μL) | 200 μL |  |
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| SEC63-20-OR | 20 (40 μL) | 200 μL |  |
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| SEC63-20-GO | 20 (40 μL) | 200 μL |  |
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| SEC63-20-GR | 20 (40 μL) | 200 μL |  |
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| SEC63-20-AQ | 20 (40 μL) | 200 μL |  |
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The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
Gene Symbol : SEC63
Gene Name : SEC63 homolog, protein translocation regulator
Chromosome : CHR 6: 107,958,277-107,867,755
Locus : 6q21
Alt. Genes : ENAM
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