This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SCRIB-20-RE | 20 (40 μL) | 200 μL |  |
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| SCRIB-20-OR | 20 (40 μL) | 200 μL |  |
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| SCRIB-20-GO | 20 (40 μL) | 200 μL |  |
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| SCRIB-20-GR | 20 (40 μL) | 200 μL |  |
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| SCRIB-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Symbol : SCRIB
Gene Name : Scribbled planar cell polarity protein
Chromosome : CHR 8: 143,815,378-143,790,919
Locus : 8q24.3
Alt. Genes : ZNF263
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