Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ROBO1-20-RE | 20 (40 μL) | 200 μL |  |
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| ROBO1-20-OR | 20 (40 μL) | 200 μL |  |
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| ROBO1-20-GO | 20 (40 μL) | 200 μL |  |
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| ROBO1-20-GR | 20 (40 μL) | 200 μL |  |
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| ROBO1-20-AQ | 20 (40 μL) | 200 μL |  |
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Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Gene Symbol : ROBO1
Gene Name : Roundabout guidance receptor 1
Chromosome : CHR 3: 797,679,97-785,972,37
Locus : 3p12.3
Alt. Genes : ZNF263
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