This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RNF19A-20-RE | 20 (40 μL) | 200 μL |  |
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| RNF19A-20-OR | 20 (40 μL) | 200 μL |  |
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| RNF19A-20-GO | 20 (40 μL) | 200 μL |  |
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| RNF19A-20-GR | 20 (40 μL) | 200 μL |  |
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| RNF19A-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Symbol : RNF19A
Gene Name : Ring finger protein 19A, RBR E3 ubiquitin protein ligase
Chromosome : CHR 8: 100,336,217-100,257,058
Locus : 8q22.2
Alt. Genes : FEM1B
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