This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RBFOX2-20-RE | 20 (40 μL) | 200 μL |  |
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| RBFOX2-20-OR | 20 (40 μL) | 200 μL |  |
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| RBFOX2-20-GO | 20 (40 μL) | 200 μL |  |
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| RBFOX2-20-GR | 20 (40 μL) | 200 μL |  |
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| RBFOX2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : RBFOX2
Gene Name : RNA binding fox-1 homolog 2
Chromosome : CHR 22: 360,288,91-357,387,35
Locus : 22q12.3
Alt. Genes : OPTN
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