RASGRP1 FISH Probe

This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
RASGRP1-20-RE 20 (40 μL) 200 μL color Request Pricing
RASGRP1-20-OR 20 (40 μL) 200 μL color Request Pricing
RASGRP1-20-GO 20 (40 μL) 200 μL color Request Pricing
RASGRP1-20-GR 20 (40 μL) 200 μL color Request Pricing
RASGRP1-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol : RASGRP1

Gene Name : RAS guanyl releasing protein 1

Chromosome : CHR 15: 385,648,05-384,880,96

Locus : 15q14

Alt. Genes : LRPPRC

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