The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RANBP17-20-RE | 20 (40 μL) | 200 μL |  |
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| RANBP17-20-OR | 20 (40 μL) | 200 μL |  |
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| RANBP17-20-GO | 20 (40 μL) | 200 μL |  |
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| RANBP17-20-GR | 20 (40 μL) | 200 μL |  |
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| RANBP17-20-AQ | 20 (40 μL) | 200 μL |  |
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The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002]
Gene Symbol : RANBP17
Gene Name : RAN binding protein 17
Chromosome : CHR 5: 170,861,881-171,300,014
Locus : 5q35.1
Alt. Genes : YAF2
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