This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RAB21-20-RE | 20 (40 μL) | 200 μL |  |
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| RAB21-20-OR | 20 (40 μL) | 200 μL |  |
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| RAB21-20-GO | 20 (40 μL) | 200 μL |  |
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| RAB21-20-GR | 20 (40 μL) | 200 μL |  |
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| RAB21-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015]
Gene Symbol : RAB21
Gene Name : RAB21, member RAS oncogene family
Chromosome : CHR 12: 717,548,62-717,934,75
Locus : 12q21.1
Alt. Genes : HIPK3
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