This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PURB-20-RE | 20 (40 μL) | 200 μL |  |
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| PURB-20-OR | 20 (40 μL) | 200 μL |  |
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| PURB-20-GO | 20 (40 μL) | 200 μL |  |
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| PURB-20-GR | 20 (40 μL) | 200 μL |  |
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| PURB-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008]
Gene Symbol : PURB
Gene Name : Purine rich element binding protein B
Chromosome : CHR 7: 448,853,84-448,762,92
Locus : 7p13
Alt. Genes : FARP1
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