The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTGER4-20-RE | 20 (40 μL) | 200 μL |  |
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| PTGER4-20-OR | 20 (40 μL) | 200 μL |  |
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| PTGER4-20-GO | 20 (40 μL) | 200 μL |  |
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| PTGER4-20-GR | 20 (40 μL) | 200 μL |  |
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| PTGER4-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
Gene Symbol : PTGER4
Gene Name : Prostaglandin E receptor 4
Chromosome : CHR 5: 406,799,29-407,409,31
Locus : 5p13.1
Alt. Genes : FEM1B
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