This gene encodes a secreted ligand of the GDNF (glial cell line-derived neurotrophic factor) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. This protein may play a role in cell death, and nervous system development and function. Elevated expression of this gene has been observed in oral squamous cell carcinoma. [provided by RefSeq, Aug 2016]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
PSPN-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
PSPN-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
PSPN-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
PSPN-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
PSPN-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a secreted ligand of the GDNF (glial cell line-derived neurotrophic factor) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. This protein may play a role in cell death, and nervous system development and function. Elevated expression of this gene has been observed in oral squamous cell carcinoma. [provided by RefSeq, Aug 2016]
Gene Symbol : PSPN
Gene Name : Persephin
Chromosome : CHR 19: 637,584,8-637,529,3
Locus : 19p13.3
Alt. Genes : LPAR6
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