Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRPF8-20-RE | 20 (40 μL) | 200 μL |  |
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| PRPF8-20-OR | 20 (40 μL) | 200 μL |  |
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| PRPF8-20-GO | 20 (40 μL) | 200 μL |  |
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| PRPF8-20-GR | 20 (40 μL) | 200 μL |  |
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| PRPF8-20-AQ | 20 (40 μL) | 200 μL |  |
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Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008]
Gene Symbol : PRPF8
Gene Name : Pre-mRNA processing factor 8
Chromosome : CHR 17: 168,488,1-165,062,8
Locus : 17p13.3
Alt. Genes : ENAM
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