This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PROKR1-20-RE | 20 (40 μL) | 200 μL |  |
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| PROKR1-20-OR | 20 (40 μL) | 200 μL |  |
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| PROKR1-20-GO | 20 (40 μL) | 200 μL |  |
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| PROKR1-20-GR | 20 (40 μL) | 200 μL |  |
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| PROKR1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016]
Gene Symbol : PROKR1
Gene Name : Prokineticin receptor 1
Chromosome : CHR 2: 686,458,21-686,555,75
Locus : 2p13.3
Alt. Genes : ABI2
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