Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis, and are the major DNA-binding proteins in the nucleus of sperm in many vertebrates. They package the sperm DNA into a highly condensed complex in a volume less than 5% of a somatic cell nucleus. Many mammalian species have only one protamine (protamine 1); however, a few species, including human and mouse, have two. This gene encodes protamine 2, which is cleaved to give rise to a family of protamine 2 peptides. Alternatively spliced transcript variants have also been found for this gene. [provided by RefSeq, Sep 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRM2-20-RE | 20 (40 μL) | 200 μL |  |
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| PRM2-20-OR | 20 (40 μL) | 200 μL |  |
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| PRM2-20-GO | 20 (40 μL) | 200 μL |  |
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| PRM2-20-GR | 20 (40 μL) | 200 μL |  |
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| PRM2-20-AQ | 20 (40 μL) | 200 μL |  |
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Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis, and are the major DNA-binding proteins in the nucleus of sperm in many vertebrates. They package the sperm DNA into a highly condensed complex in a volume less than 5% of a somatic cell nucleus. Many mammalian species have only one protamine (protamine 1); however, a few species, including human and mouse, have two. This gene encodes protamine 2, which is cleaved to give rise to a family of protamine 2 peptides. Alternatively spliced transcript variants have also been found for this gene. [provided by RefSeq, Sep 2015]
Gene Symbol : PRM2
Gene Name : Protamine 2
Chromosome : CHR 16: 112,764,79-112,756,35
Locus : 16p13.13
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