This gene encodes a member of the heterogeneous family of proline-rich salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid and submandibular/sublingual glands. In western population this locus is commonly biallelic and encodes proline-rich protein (PRP) isoforms, PRP-1 and PRP-2. The reference genome encodes the PRP-1 allele. Certain alleles of this gene are associated with susceptibility to dental caries. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. [provided by RefSeq, Oct 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRH2-20-RE | 20 (40 μL) | 200 μL |  |
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| PRH2-20-OR | 20 (40 μL) | 200 μL |  |
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| PRH2-20-GO | 20 (40 μL) | 200 μL |  |
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| PRH2-20-GR | 20 (40 μL) | 200 μL |  |
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| PRH2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the heterogeneous family of proline-rich salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid and submandibular/sublingual glands. In western population this locus is commonly biallelic and encodes proline-rich protein (PRP) isoforms, PRP-1 and PRP-2. The reference genome encodes the PRP-1 allele. Certain alleles of this gene are associated with susceptibility to dental caries. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. [provided by RefSeq, Oct 2015]
Gene Symbol : PRH2
Gene Name : Proline rich protein HaeIII subfamily 2
Chromosome : CHR 12: 109,292,35-109,348,44
Locus : 12p13.2
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