PPP1R16A FISH Probe

Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c. [provided by RefSeq, Jul 2016]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
PPP1R16A-20-RE 20 (40 μL) 200 μL color Request Pricing
PPP1R16A-20-OR 20 (40 μL) 200 μL color Request Pricing
PPP1R16A-20-GO 20 (40 μL) 200 μL color Request Pricing
PPP1R16A-20-GR 20 (40 μL) 200 μL color Request Pricing
PPP1R16A-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c. [provided by RefSeq, Jul 2016]

Gene Details

Gene Symbol : PPP1R16A

Gene Name : Protein phosphatase 1 regulatory subunit 16A

Chromosome : CHR 8: 144,477,986-144,502,120

Locus : 8q24.3

Alt. Genes : CLEC3A

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